Endocrine Abstracts

Purpose: The purpose of this study was to evaluate the prevalence and characteristics of individuals with spine–femur bone mineral density (BMD) discordance and to examine whether trabecular bone score (TBS) is associated with major and minor BMD discordance in postmenopausal women.Methods: This retrospective study included 533 healthy postmenopausal women (median age, 60 years; range, 55–82 years) who visited our hospital for a health check-up...

Somatostatin analogues (SSA) are widely used for the treatment of patients with acromegaly, and the responses are variable. We investigated the possible predictive factors of the response to SSA therapy in Korean acromegalic patients. Twenty-eight patients were retrospectively analysed, who were treated by surgery and adjunctively SSA. Somatostatin suppression tests (SST, hourly GH measurements for 3 h following 100 μg somatostatin injection) were done before SSAs were gi...

Objectives: Immune checkpoint inhibitors (ICIs) have demonstrated stunning effects in many cancer types albeit its immune-related adverse outcomes such as hypophysitis, adrenalitis, and thyroiditis. Despite the significant increase in ICIs use in Korea, there still is a lack of clarification about the actual prevalence and risk factors of ICI-associated thyroid diseases.Methods: In this nationwide cohort study, 12,079 lung cancer patients were extrapolat...

Objectives: Radioactive iodine (RAI) therapy has potential therapeutic effects in treating Graves’ disease (GD). However, whether RAI therapy for GD can increase cancer risk remains a controversial issue in medicine and public health.Methods: Using the Korean National Health Insurance Service-National Health Information Database (NHIS-NHID, 2002–2020), we investigated hazard ratios (HRs) of overall and site-specific cancer associated with RAI i...

Objective: Brachial-ankle pulse wave velocity (baPWV) was used as a noninvasive marker of arterial stiffness. The aim of this study was to assess the association between arterial stiffness and cause specific mortality in patients with type 2 diabetes mellitus (T2DM).Methods: This multicenter prospective observational study analyzed 2,320 patients with T2DM. The patients were divided into two groups according to baPWV (cutoff baPWV of 1,750 cm/s). Causes ...